Neuroscience Reagents and Kits
Cell Signaling Technology PathScanR Nestin Sandwich ELISA Kit 50 Kit
PathScanR Nestin Sandwich ELISA Kit 50 Kit
Cayman Chemical CyclIc dIGMPHRP Tracer 100dtn
A synthetic peptide fragment of vitronectin induces attachment and cell spreading of isolated human osteogenic cells when applied to cell plates at 9.1 Ug/cm2 induces osteogenesis of human skin-derived mesenchymal precursors and MC3T3-E1 mouse calvarial osteoblast precursors decreases IL-1a-induced bone loss and decreases the number of calvarial osteoclasts in mice increases bone mineral density and decreases trabecular bone loss in a mouse model of ovariectomy-induced bone loss
Cayman Chemical CyclIc dIAMPHRP Tracer 100dtn
An antimicrobial peptide and a derivative of LL-37 active against E. coli P. aeruginosa C. albicans and A. niger (MICs 2 3 6 and 18 UM respectively) PLGA microspheres containing OP-145 prevent biofilm formation in a mouse model of bone infection induced by surgical femoral fracture followed by bacterial inoculation at the fracture site
Cayman Chemical Latnoprost AChE Tracer 100dtn
A multi-kinase inhibitor inhibits VEGFR2 PDGFRB FLT3 and c-Kit (IC50s 1.12 0.13 0.63 and 0.14 nM respectively) and is selective for these kinases over RET and AMPKa1 (IC50s 74.1 and 352.2 nM respectively) inhibits VEGF-induced proliferation of HUVECs (IC50 31 nM) decreases VEGF-induced capillary tube formation in HUVECs at 1 UM reduces FBS-induced migration of HUVECs at 0.01 or 0.1 UM reduces tumor volume and growth alone and in combination with gefitinib in an HCC827 NSCLC mouse xenograft model at 80 mg/kg per day
Cayman Chemical CyclIc GMP AChE Tracer 500dtn
A steroidal glycoside with diverse biological activities reduces the proliferation of LNCaP and T47D cancer cells (IC50s 32.1 and 27.5 UM respectively) inhibits TNF-a-induced nuclear translocation of NF-KB in HaCaT keratinocytes at 50 nM decreases AST serum levels in a mouse model of carbon tetrachloride-induced liver injury at 0.1 mg/kg topical administration reduces ear epidermal thickness and scaling as well as leukocyte and macrophage infiltration in an imiquimod-induced mouse model of psoriasis at 5 mg/kg
Cayman Chemical 8-Isoprostn AChE Tracer 500dtn
A cardiac glycoside with cardiotonic and antiarrhythmic activities inhibits Na /K -ATPase in an isoform-specific biphasic manner with IC50 values of 0.298 and 410 UM for the high- and low affinity human erythrocyte isoenzymes respectively and 1.18 and 28.5 UM for the high- and low affinity porcine cerebral cortex isoenzymes respectively increases contractility and rhythmicity in isolated guinea pig heart in a concentration-dependent manner a degradation product of digoxin